Credit Units: 2
Lecturer: Dr. IKWUKA A.O. (MD, Sp. Cert., PhD Medicine) Email Id: email@example.com, College of Health Sciences, Department of Pharmacy & Pharmaceutical Sciences.
This course is designed to enable the dental therapy student to acquire knowledge and apply the principles of pharmacology and therapeutics in drug administration and its dental implications. The course will also equip the dental therapy student with knowledge of patient safety issues through diagnosis and reporting of adverse events. Students shall also engage in the discussion of current primary research literature in the field of pharmacology and therapeutics.
This course includes the following lecture themes:
- Sources of drugs: plant, animal, synthetic, bacteria and fungi; General principles of
pharmacology: pharmacokinetics and pharmacodynamics
The drugs listed below will be discussed under the following headings:
- Introduction/group 2. Mechanism of action 3. Pharmacological effects 4. Indication 5. Side effects 6. Contra-indications 7. Drug interactions 8. Dosage 9. Routes of administration 10. Dental implications
- Analgesics – Opiates: morphine, pethidine; Salicylates: aspirin; Non-steroidal anti- inflammatory agents: Aspirin, ibuprofen and diclofenac; Miscellaneous: paracetamol.
- Hypnotics and sedatives: diazepam, barbiturates.
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- Drugs acting on the respiratory system – Bronchodilators: salbutamol, aminophylline, Analeptics/respiratory stimulants: nikethamide; Expectorant/mucolytics: benylin; Cough suppressants: codeine linctus.
- Drugs used in infections: Antibacterial drugs – Penicillins: benzylpenicillin, amoxicillin, cloxacillin; Tetracyclines; Aminoglycosides: streptomycin, gentamycin, neomycin, kanamycin; Macrolides: erythromycin; Cephalosporins: cefotaxime, cefuroxime, cephalexen; Sulphonamides: sulphadimidine, cotrimoxazole; Chloramphenicol; Antituberculous drugs: rifampicin, isoniazid; Antileprotic drugs: dapsone, clofazimine; Antiprotozoal drugs: metronidazole; Antimalarials: halofantrine hydrochloride, fansidar, artesunate, amodiaquine; Amoebicides: metronidazole; Antifungal drugs: nystatin, miconazole, griseofulvin, clotrimazole.
- Antiretrovirals (ARVs) in use (country-specific): 1st line and 2nd line drugs, Antiretrovirals used in Prevention of mother-to-child transmission (PMTCT); Antihelminthics: mebendazole, albendazole. Steroids: dexamethasone, hydrocortisone.
- Cytotoxic drugs – Alkylating agents: busulphan; Antimetabolites: fluorouracil, methotrexate, cytosine; Alkaloids: vincristine; Antibiotics: doxorubicin (Adriamycin).
- Drugs acting on the digestive system – Antacids: aluminium hydroxide, magnesium trisilicate; Antispasmodics or Spasmolytics: hyoscine butylbromide; Histamine (H2) – receptor blockers: cimetidine, ranitidine; Proton pump inhibitor: omeprazole; Cytoprotectives: misoprostol; Laxatives: bisacodyl, magnesium sulphate, liquid paraffin; Antiemetics: promethazine hydrochloride, metoclopramide, hyoscine, avomine.
Methods of Instruction:
- Discussion groups
- Guest lectures
- Projects (e.g. case studies, poster presentation, seminar presentation)
- Reading of articles from relevant scientific journals
Methods of Course Assessment: Evaluation will be carried out in accordance with the university policy. The lecturer will present a written course outline with specific evaluation criteria at the beginning of the semester. Evaluation will be based on the following:
Individual Works/Tasks 10
Class Tests 10
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Class Assignments 10
Final Examination 70
Pre-requisite courses: Medical Genetics, Human Physiology, Biochemistry, Microbiology
Co-requisite course(s): None
Recommended Reference Materials: Textbooks
- Karen Whalen, et al (2019) Lippincott® Illustrated Reviews Pharmacology, 7th edition 2. Katzung Bertram G. (2018) Lange® Basic & Clinical Pharmacology, 14th edition 3. Hilal-Dandan Randa, Brunton Laurence L. (2013) Goodman & Gilman’s Manual of
Pharmacology and Therapeutics, 2nd edition 4. Chekman Ivan, et al (2006) Pharmacology, 1st edition 5. Stefanov O., Kucher V. (2004) Pharmacology with General Prescription, 1st edition
- Journal of Pharmacology and Pharmacotherapeutics 2. Journal of Experimental Pharmacology 3. Biomedical and Pharmacology Journal
Web 1. www.drugs.com
- www.medscape.com 3. www.en.wikipedia.org
Please click on the course content tab to have access to all required materials for this course.